DHEA Oral Supplement Review

Meet Our Experts
Cleveland Clinic, ranked as one of the nation’s best hospitals overall (4th in the country) by U.S. News & World Report 2013-14, is proud to offer expert advice and guidance to help you on your journey to wellness.
Meet Our Experts
DHEA is a naturally occurring steroid, not to be confused with the omega 3 fatty acid DHA
  Evaluated for:
Effectiveness Rating Effectiveness Rating
-1 (Possibly Ineffective)
-1 (Possibly Ineffective)
-1 (Possibly Ineffective)


  • DHEA (Dehydroepiandrosterone) is made in the adrenal glands and then converted into female and male sex hormoned like estrogen and androgen. Levels of DHEA normally begin to decrease around age 30.
  • DHEA may be useful in treating adrenal insufficiency, depression, and lupus (SLE). It is has been used to improve depression specifically in HIV/AIDS patients. DHEA has been used by women with adrenal or androgen insufficiency to improve their overall well-being and sexual function.
  • Because DHEA has estrogen-like effects, some researchers believe that DHEA may have benefits in menopause similar to hormone replacement therapy (HT) with estrogen and progestin. However, unlike HT, DHEA also substantially increases androstenedione and testosterone, two male hormones.
  • DHEA is also being investigated as a prescription drug for treating systemic lupus erythematosus (SLE) and improving bone mineral density in women whose lupus is being treated with steroids.


  • There are concerns that DHEA may promote prostate, ovarian, and breast cancers. It should therefore be taken only with physician monitoring, and never by children or in pregnancy.
  • DHEA may cause breast tenderness and facial hair in women. It may also interfere with insulin metabolism and cause acne.
  • A 2-yr Mayo study (2006) found no effect on endurance, muscle mass, fat mass, insulin sensitivity, and quality of life.
  • Long term use may cause serious side effects. These effects occur more frequently at doses higher than 50mg daily.

People with a history, or at high risk, of developing hormone-related cancers should not use DHEA. Hormonal stimulation of tumors and cancer are side effects. Banned by NCAA, Olympics. Concerns about increasing growth of endocrine responsive tumors. While available OTC in USA, requires a prescription in most other countries.

CONCLUSION:We do not recommend the use of this product.

“DHEA.” ConsumerLab.com. ConsumerLab.com LLC, 2013. 14 June 2013
“DHEA.” Natural Standard –The Authority on Integrative Medicine. Natural Standard, 2013.
“DHEA.” Natural Medicines Comprehensive Database. Therapeutic Research Faculty, 2013. 8 November 2013.

Untitled Document
Get Your Daily Tip
Start living healthier with our FREE daily wellness tips!