Estrovera Supplement Review

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  Evaluated for:
Effectiveness Rating Effectiveness Rating
Managing menopausal symptoms, including hot flashes and mood disturbances
+2 (Moderate Evidence)


  • Estrovera shows strongly positive results for the treatment of menopausal symptoms such as hot flashes, mood swings and anxiety.
  • The study’s results were almost too good to be true. In the past, the only intervention to achieve similar response rates has been treatment with estrogen itself.
  • Estrovera has a very low incidence of adverse side effects.
  • Animal studies showed no association with breast or uterine cancers.
  • The risks associated with this supplement are minimal.


  • These results were based on single clinical trial, which was sponsored by the manufacturer of the supplement. Future trials by independent research groups are needed to confirm benefits.
  • It can take up to 6 weeks to experience the benefits of this therapy.
  • Although estrovera does not appear to stimulate estrogen receptors related to the development of breast cancer, additional safety data and research are needed to prove its safety.

To be safe, estrovera should not be used in women with a history of breast or endometrial cancer.

DOSAGE:One Estrovera tablet daily.

CONCLUSION:We conclude that estrovera is a safe and effective product for managing menopausal symptoms. Although estrogen has long been considered the most effective treatment for menopausal symptoms, there is a slight risk associated with taking hormones. To date, no other therapies have been found to be as effective. If you elect to try estrovera, remember to include it in your list of medications when you visit your doctor and other health care providers.

Heger, M. et al. Efficacy and safety of a special extract of Rheum rhaponticum (ERr 731) in perimenopausal women with climacteric complaints: a 12-week randomized, double-blind, placebo-controlled trial. Menopause: The Journal of The North American Menopause Society (2006) 13(5): 744-759
Kaszkin-Bettag, M. et al. The special extract ERr 731 of the roots of Rheum rhaponticum decreases anxiety and improves health state and general well-being in perimenopausal women. Menopause: The Journal of The North American Menopause Society (2007) 14(2): 270-283
Hasper, I. et al. Long-term efficacy and safety of the special extract ERr 731 of Rheum rhaponticum in perimenopausal women with menopausal symptoms. Menopause: The Journal of The North American Menopause Society (2008) 16(1): 1-15

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