Irvingia Supplement Review

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  Evaluated for:
Effectiveness Rating Effectiveness Rating
Weight loss
+1 (Slight Evidence)
Increasing good HDL cholesterol
+1 (Slight Evidence)


  • In just 10 weeks, people taking this product saw a ten percent decrease in weight and waist measurements.
  • In this same amount of time people experienced almost a 50 percent increase in good cholesterol with a 50 percent decrease in inflammatory c-reactive protein.
  • African mango is commonly eaten locally without negative side effects.
  • Dr. Kenneth Bloom of Wake Forrest University School of Medicine, an independent scientist associated with the 2009 report, viewed and analyzed the original data. He is confident of the results.
  • The insoluble fiber in the fruit has properties that affect leptin and adiponectin, resulting in weight loss.


  • The researcher who conducted the studies is the Chief Scientific Officer of the company selling the product. This conflict of interest may bias the study. This product needs to be tested by an independent research group.
  • The biologically active ingredients and the mechanisms for achieving the results are not known.
  • I am skeptical about the ability of a supplement to produce such huge improvements in LDL cholesterol (30-40%) and good HDL cholesterol (50%).

It seems safe enough but, as always, consult your doctor before trying a new weight loss supplement.

DOSAGE:Take 150 mg 30 to 60 minutes before lunch and dinner.

CONCLUSION:Weight loss is best brought about through healthy lifestyle changes in eating and activity patterns. This product does not seem risky to us, but always be careful when you try something new.

“Irvingia Gabonensis.” Natural Standard –The Authority on Integrative Medicine. Natural Standard, 2013.
“Irvingia Gabonensis.” Natural Medicines Comprehensive Database. Therapeutic Research Faculty, 2013. 8 November 2013.
Hasani-Ranjbar, S. et al. A systematic review of the efficacy and safety of herbal medicines used in the treatment of obesity. World Journal of Gastroenterology (2009) 15(25): 3073-3085
Panthong, A. et al. Analgesic, anti-inflammatory and venotonic effects of Cissus quadrangularis Linn. Journal of Ethnopharmacology (2007) 110, 264-270
Oben, J. et al. The use of a Cissus quadrangularis/Irvingia gabonensis combination in the management of weight loss: a double-blind placebo-controlled study. Lipids in Health and Disease (2008) 7:12
Singh, G. et al. Constituents of Cissus quadrangularis. Natural Product Research (2007) 21(6), 522-528
Mehta, M. et al. Determination of Marker Constituents from Cissus quadrangularis Linn. and their Quantitation by HPTLC and HPLC. Phytochemical Analysis (2001) 12, 91-95
Oben, J. et al. The effect of Cissus quadrangularis (CQR-300) and a Cissus formulation (CORE) on obesity and obesity-induced oxidative stress. Lipids in Health and Disease (2007) 6:4
Oben, J. et al. The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome. Lipids in Health and Disease (2006) 5:24

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