Raspberry Ketones Supplement Review

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Raspberry Ketones
  Evaluated for:
Effectiveness Rating Effectiveness Rating
Weight Loss
0 (Effectiveness Unclear)

PRO

  • Found in red raspberries, raspberry ketones are aromatic compounds with a similar chemical structure to capsaicin, which is found in hot peppers.
  • Raspberry ketones decreased fat accumulation in mice fed high-fat diets.
  • Raspberry ketones lowered the weight and fat content of mouse livers. Future research is needed to determine whether this might apply to people with fatty liver disease.
  • Topical raspberry ketones may improve skin elasticity and increase hair growth in people with hair loss.

CON

  • Raspberry ketones are used widely in food, cosmetics, and perfumes. Although no specific risks have been identified to date, individuals should remain alert to a possible allergic reaction to the product.
  • Of greater concern, no studies have been undertaken to assess for weight loss in human subjects. Studies of mice and rats showed weight loss, or decreased weight gain with overfeeding.
  • On the basis of both its cost and the lack of sufficient research to support its weight loss claim, we recommend greater study of raspberry ketones before its use becomes widespread.

* *ADVISORY* *
If you elect to try raspberry ketones, observe for any changes to your health.

DOSAGE:There is currently no established dosage for humans.

CONCLUSION:We conclude that while raspberry ketones show promise for aiding weight loss efforts, there is not enough evidence for us to recommend its use. If you do elect to try it, please discuss your decision with your doctor, and observe carefully for any changes to your health.

REFERENCES
“Raspberry Ketone.” Natural Standard –The Authority on Integrative Medicine. Natural Standard, 2013.
“Raspberry Ketone.” Natural Medicines Comprehensive Database. Therapeutic Research Faculty, 2013. 8 November 2013.
Morimoto, C. et al. Anti-obese action of raspberry ketone. Life Sciences (2005) 77, 194-204
Ogawa, Y. et al. Effect of essential oils, such as raspberry ketone and its derivatives, on antiandrogenic activity based on in vitro reporter gene assay. Bioorganic & Medicinal Chemistry Letters (2010) 20, 2111-2114
Harada, N. et al. Effect of topical application of raspberry ketone on dermal production of insulin-like growth factor-I in mice and on hair growth and skin elasticity in humans. Growth Hormone & IGF Research (2008) 18, 335-344
Park, K.S. et al. Raspberry Ketone Increases Both Lipolysis and Fatty Acid Oxidation in 3T3-L1 Adipocytes. Planta Med (2010) 76: 1654-1658
Wang, L. et al. Raspberry Ketone Protects Rats Fed High-Fat Diets Against Nonalcoholic Steatohepatitis. Journal of Medicinal Food (2012) 15(5):495-503
Vargas, R. et al. Response of Melon Fly (Diptera: Tephritidae) to Weathered SPLAT-Spinosad-Cue-Lure. J Econ Entomol (2010) 103(5):1594-1602


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