* *ADVISORY* *Due to the serious nature of depression, people should use SAM-e only with the knowledge and under the guidance of their mental health specialist/provider.
DOSAGE:For depression, take 400 mg three to four times daily. For osteoarthritis, take 400 mg two to three times a day.
CONCLUSION:We conclude that SAM-e is a safe and effective product for the treatment of depression and osteoarthritis. If you elect to try it, remember to include it in your list of medications when you visit your doctor and other health care providers.
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