Bromelain Supplement Review

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  Evaluated for:
Effectiveness Rating Effectiveness Rating
+2 (Moderate Evidence)
+2 (Moderate Evidence)


  • Bromelain is a digestive enzyme that is extracted from the pineapple. It is present in all parts of the plant, with the stem being the most common commercial source of bromelain.
  • Bromelain appears to have anti-inflammatory properties. It has demonstrated effectiveness as an adjunct to conventional treatment for decreasing pain associated with inflamed joints (arthritis) and upper respiratory passages (sinusitis).
  • Bromelain is sometimes used in a tenderizer in cooking. In meat marinades, it helps to tenderize meat by breaking down the protein-rich fibers. Sensitive to heat, bromelain becomes ineffective as a tenderizer once it has been cooked.
  • Bromelain is generally regarded as safe.


  • Side effects may include occasional mild gastrointestinal distress or allergic reactions for those with pineapple allergies, yet these risks are low if taken in proper doses.
  • More studies are needed to clearly establish effectiveness.
  • Its safety in children, in pregnant or nursing women, and in liver or kidney disease has not been established.

Bromelain might increase the effect of blood thinners like coumadin and heparin, of sedatives such as benzodiazepines, and of certain antibiotics such as amoxicillin and tetracycline.

DOSAGE:250 to 750 mg, two or three times a day.

CONCLUSION:We conclude that bromelain is a safe and effective product for arthritis pain and sinusitis. If you elect to try it, remember to include it in your list of medications when you visit your doctor and other health care providers.

“Bromelain.” Natural Standard –The Authority on Integrative Medicine. Natural Standard, 2013.
“Bromelain.” Natural Medicines Comprehensive Database. Therapeutic Research Faculty, 2013. 8 November 2013.
Bromelain. EBSCO Publishing (2011) 1-5

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